Biography
I am a lecturer at Virology and immunology unit, National Cancer Institute (NCI), Cairo University, Cairo, Egypt since 2020, with 14 years’ experience. Since my graduation, in addition to my cancer related work, I have participated in numerous virus related studies, namely HCV, SARS-CoV2, Human papillomavirus. My research in cancer focused on finding some novel biomarkers and genetic mutations to improve diagnosis, treatment and prevention of cancer. In addition, I am interested in studying the role of viruses and genetic mutations involved in cancer development in order to find a way to stop this disease.
During my master, I have studied some potential biomarkers in Hepatocellular Carcinoma patents (HCC) with HCV infection; those biomarkers included some miRNAs, IL8, proteasome, sICAMs and STNF-RII. In addition, I have participated in a previous Gilead project which investigated the Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed Dose Combination in the Treatment of Hepatitis C Virus (HCV) Infection in Pediatric Subjects Undergoing Cancer Chemotherapy since 2017, project ID: GS-US-337-1904. During COVID-19 outbreak, I have participated in investigating the molecular identification and classification of the novel coronavirus among Egyptian patients, as well as investigating the immune repertoire profile in Egyptian COVID-19 patients using Next Generation sequencing.
During my doctorate, I have studied the genetic profile at different stages of colorectal carcinogenesis process using multigene panel sequencing. Also, I have participated in a previous project funded by STDF entitled “ Advanced Biomedical Genomics Center-Sequencing the first 200 Egyptian Genome” since 2019 as well as another complementary project entitled “ Accredited National Cancer Institute molecular biology laboratory” since 2021 .Moreover, I participated in studying the relation between the microbiome as well as viral co-infection, of either oncogenic or non-oncogenic viruses with genetic mutations in Egyptian patients with colorectal cancer.
Recently, I have been awarded the Cairo University Encouragement award in the field of biological sciences.